February 01, 2012

Female Infertility Treatment

Although it has more than one year without using contraception mating, as much as approximately 7% of couples do not get a descent. Various means have been taken, ranging from simple to the in vitro fertilization (IVF) and intra-sitoplama sperm injection (SSIS / ICCI), but still have not got pregnant. Apparently many molecular biological processes is still unknown and still takes a long time to learn it. Nidasi and trophoblast invasion in the early embryo growth, influenced by various factors such as paracrine hormone fluctuations, local tissue reactions occurring within the trophoblast and desidu, as well as the role of metalloproteinases and adhesive proteins. All of these factors are only found in the tissue and the levels in the serum can not be checked. Therefore, to look for causes of infertility are forced to use conventional methods, which can also help some women.

History is still a good way to look for causes of infertility in women. Many important factors associated with infertility can be asked to the patient.

Age of patients is very important to know, because with increasing age, the more difficult to get the child. Difficulty in getting a child not because the woman has become old, but more due to the reduced quality of the woman's egg cell. When done egg donation, for example in a menopausal woman, the woman would get pregnant and her pregnancy is progressing well. This suggests that instead of the uterus that causes women to not be pregnant but the ability of the woman's egg to be fertilized has been reduced
Theoretically, as long as the ovaries are normal, then it is likely to become pregnant is always there. Therefore do not occasionally say About a woman aged 40 years might not be pregnant. Pregnancy is possible, but likely not so great. By act of IVF did not give satisfactory results.

History of disease, or previous surgery can provide information about the causes of infertility. History of previous diseases such as appendicitis, peritonitis, salpingitis can cause abnormalities in the tube. In the anamnesis should also ask whether the patient is suffering from diseases such as hypothyroidism, hyperthyroidism, pituitary disease, and suprarenal, yagn DAPT cause infertility. Diabetes is also one of the causes of infertility.

Weight loss and changes in body weight (too fat, too skinny) will affect the treatment of infertility. Subcutaneous fat contain the aromatase enzyme, so that androgen is converted to estrogen. High estrogen to suppress FSH and LH expenditure. Moreover, high estrogen increases LH secretion. High LH suppresses the activity of the enzyme aromatase that androgens can not be converted into estrogen. In obese women often found insulin resistant. Insulin triggers the consistency of DHEA in the suprarenal, resulting in hyperandrogenaemia. Androgen levels in follicular fluid and serum in high and this causes the follicle atresia. Keep in mind also that DHEA is a precursor that is used to mensistensis other types of steroid hormones (estrogen, progesterone, and androgens).

Leptin cells suppress the production of neuropeptide Y in the hypothalamus. Usually, this neuropeptide reduces hunger. Because leptin in obese women suppress the production of neuropeptide Y, then the patient will always feel hungry, so the porch body will continue to grow. Leptin also triggers the FSH and LH. High LH levels of androgens to estrogens inhibit change and naturally rapid increase in androgen levels. Emaciation due to chronic malnutrition does not cause the formation of fat and leptin, so there is no expenditure of FSH and LH stimulation. The result is anovulation until amenorrhoea. Therefore, the regulation of body weight is extremely important in the treatment of female infertility.

With a history can also be known endokrinologik abnormalities. Presence of hirsutism, acne, or seborrheic indicates hyperandrogenaemia, or abnormalities in the thyroid gland function. The discovery of galactorrhea is a sign of hyperprolactinemia.

There should also note the pattern of life of patients with infertility. Alcohol, for example, can inhibit the action of the enzyme sulfatase and aromatase enzyme, resulting in interference with the hormonal system. Nicotine reduces blood flow and accelerate the destruction of genitalia tool hormones. Stress is also a causative factor for difficulty having children. Stress triggers the corticotropin releasing factor (CRF). CRF expenditure suppress LH and GH and triggers the pro-opiomelanocortin (POMC) in pituitary cells kortikotrop front. Intermedia in the pituitary, POMC this will be resolved into two parts, namely lipoprotein and endorphin. Endorphin has antigonadotrop effect and is a dopamine antagonist. In people who use marijuana frequently found morphine or menstrual disorders.

Disorders of sexual relations can cause infertility, such as incomplete penetration into the vagina, very rarely have sex, or vaginismus. Nowadays women often washes her intimate organs and the surrounding area with antiseptic fluids. This habit can cause changes in cervical mucus which becomes inhospitable to sperm. In the vagina there are various types of microorganisms. These microorganisms keep the vagina is acidic, so it serves to protect the vagina from infection. Microorganisms are also known as "good" bacteria. Cleaning the sex organs with antiseptic fluids it will cause the bacteria are "good" is dead, will cause the bacteria are "bad" breed. Using deodorant perfumes in sex organs also made a "good" bacteria die. It should be encouraged to use underwear made of cotton, and do not use the pants are too tight, so as not to cause a feeling wet all the time.

Male Infertility Treatment

Infertility is a condition of married couples more than one and a half years without contraception, no children. One-half-year figures set, since it is usually 85 percent of couples in a year and half already have children. This means, 15 percent of couples of childbearing age have this problem.

Reality shows, 40 percent of the problems that make it difficult to have children there are in women, 40 percent in men, and 30 percent in both. So, do not correct the assumption that women are responsible for the difficulty of getting children.

Although the problem of infertility had no effect on daily physical activity and not life-threatening, for many couples this is a great impact on family life. Surely psikokultural factors influencing attitudes towards the couple this problem, including efforts irrational to have children. Indeed, what the patient can not be blamed entirely, as though cutting edge of medical science can not answer satisfactorily the problem of infertility.

Examination of men with infertility doctors performed just like in people in other diseases, but accompanied by examination of sperm. These hearings to see the potential of male to fertilize. When there are problems, then do the other more in-depth examination.


As well as prevention of disease in general, the first attempt ever to be undertaken is to find the cause of infertility. 
The most common cause of male infertility is widening vein / veins around the testicles is called a varicocele. On physical examination, this is found in the form of a lump at the top of the testicles will grow real big and when to push. The more frequent contact with the left scrotum.
Most of the varicocele is not accompanied by pain, although some are complaining sore in the area. Varicocele was found in 40 percent of patients. These findings are not much different from the findings of one of the renowned infertility prevention centers at Baylor College of Medicine, United States, where 42 percent.

Other causes of infertility in men is a blockage / obstruction in the vas deferens. So although the spermatozoa produced by both, remains to be channeled. Usually this is caused by the occurrence of congenital infection and because it does not formed part of the vas deferens. This occurred in 15 percent of patients. In the remaining 20 percent, infertility caused by various factors, such as hormonal disorders, congenital abnormalities, the influence of drugs, erectile or ejaculatory disturbances, radiation, pesticide poisoning, immunological disorders, surgery in the pelvic area, and others.

By knowing the factors that cause it, some things can be done to prevent or cope with infertility.

Prevention of infertility

Some things you can do : various kinds of infections are known to cause infertility, especially infection of the prostate, testes, and vas deferens. Therefore, any infection in this area should be taken seriously.
Some substances can be toxic to the growth of sperm. Many studies have shown adverse effects of smoking on sperm count and quality. Although each study is different in determining the amount of cigarettes that effect, is enough reason for men with sperm count and quality less to quit smoking.
Alcohol in large quantities associated with lower testosterone levels which would interfere with the growth of sperm. Marijuana is also known as one of the causes of growth disorders of sperm, so the cessation of the use of marijuana and alcohol is a preventive effort to infertility.

Quite a lot of drugs that affect the sperm. Therefore, tell me more about a drug that has been and is being used to help your doctor.

The best mitigation is to deal with the cause. Unfortunately, not all causes are known and vice versa is quite a lot of people with a known cause, but can not completely overcome.
Infertility is no known cause is a significant problem because it covers 20 percent of sufferers. Abatement in the form of several kinds of drugs, which had raised the amount of experience and quality of sperm. But most of the research done by using a comparison, showed no significant improvement. Effort to find the cause of the chromosome level and success of genetic manipulation seems to be a point of hope in the future.

A blockage in the vas deferens can be ascertained only by surgery. If the blockage is so severe, with the aid of a microscope can be operated corrections. At the same operation, can also be ascertained whether or not the production of sperm in the testicles.

In accordance with the abnormalities are found, then other causes can be overcome by correcting the hormonal and cessation drugs suspected of causing sperm disorders. However, efforts in the above there are times when not managed to improve the quality and quantity of sperm, so that assisted reproduction techniques are required. Included in this is relief insemination and in-vitro insemination (IVF / IVF), which greatly helps to overcome male infertility problems.

For example, men with only 5-10 million sperm / cc (from the normal 20 million) can try artificial insemination. IVF requires only 500,000 sperm with 30-35 percent pregnancy rate. The most remarkable progress in the last 7-8 years is the technique of IVF with ICSI (Intra cytoplasmic Sperm Injection) which only requires a few spermatozoa to be injected into the mother's egg cell. The success rate is almost the same.

Obvious explanation

Such a cursory overview of infertility problems in men. Enterprises have offspring that had lasted for centuries would indeed continue. Various advances have been achieved although there is one thing that remains, that is such great expectations of the patient. Sometimes this led to the choices made without consideration mature.

Therefore, always ask your doctor a clear explanation about the therapies offered, complete with the possibility of success. This way you can be more rational conduct all examinations and treatment, excessive or hopeless despair.

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